Te wehenga o nga waahanga anticoagulant me te fibrinolytic mai i te Agkistrodon acutus venom me o raatau paanga ki te punaha coagulation
Whaainga: Ki te ako i te paanga o te thrombin kua purea penei i te enzyme me te plasmin mai i Agkistrodon acutus venom ki te punaha whakaheke toto.
Tikanga: Ko te Thrombin penei i te enzyme me te plasmin i wehea ka purea mai i te paihana o Agkistrodon acutus na DEAE Sepharose CL-6B me te Sephadex G-75 chromatography, a ko o raatau paanga ki nga tohu o te punaha coagulation i kitea i roto i nga whakamatautau vivo.Hua: Ko te Thrombin penei i te enzyme me te plasmin i wehea mai i te paihana o Agkistrodon acutus, a ko o raatau taumahatanga irapoi i te 39300 me te 26600, ia, ko nga thrombin rite te enzyme me te plasmin mai i te Agkistrodon acutus venom ka taea te whakaroa i te wa katoa o te toto coagulation, kua whakahohehia te waahanga prothrombin te wa, te wa thrombin me te wa prothrombin, me te whakaiti i te ihirangi o te fibrinogen, engari he kaha ake te paanga o te thrombin rite te enzyme, ko te plasmin e whakaatu ana i te paanga anticoagulant anake i te horopeta nui ake, a he pai ake te whakakotahitanga o nga mea e rua i to raatau whakamahi kotahi.
Whakamutunga:
Ko te Thrombin rite te enzyme me te plasmin mai i te Agkistrodon acutus venom ka pa ki te punaha whakaheke toto i roto i nga kararehe, a ko te whakakotahitanga o enei e rua ka kitea he hua anticoagulant.
Wā tuku: Mei-10-2023